Several renal disorders are inherited and can be traced back to specific genetic anomalies. Some of the most common hereditary renal disorders include:
Alport Syndrome: Caused by mutations in the COL4A5 gene, affecting the type IV collagen in the kidney's glomerular basement membrane. Fabry Disease: Linked to mutations in the GLA gene, resulting in the buildup of globotriaosylceramide in renal cells. Nephronophthisis: Associated with mutations in several genes, including NPHP1, leading to progressive kidney failure.