Individuals at higher risk for NSAID-induced renal complications include:
Those with pre-existing renal diseases such as CKD or glomerulonephritis. Patients with conditions that reduce kidney perfusion, such as heart failure or liver cirrhosis. People with diabetes, especially if they have diabetic nephropathy. Elderly individuals, as kidney function declines with age. Individuals taking other medications that affect kidney function, such as diuretics or ACE inhibitors.
