What are the Risks for Patients with Renal Disorders?

For individuals with pre-existing renal disorders, the use of NSAIDs can exacerbate kidney problems. Risks include:

Acute Kidney Injury (AKI): Sudden loss of kidney function that can occur even with short-term use of NSAIDs.
Chronic Kidney Disease (CKD): Long-term use of NSAIDs can accelerate the progression of CKD.
Electrolyte Imbalance: NSAIDs can interfere with the kidneys' ability to maintain electrolyte balance, leading to conditions like hyperkalemia.
Interstitial Nephritis: An inflammatory condition affecting the kidney's interstitial tissue, which can be triggered by NSAIDs.