Are there safer alternatives to nephrotoxic drugs?

Yes, there are often safer alternatives to nephrotoxic drugs. For example, acetaminophen can be used instead of NSAIDs for pain relief in patients with kidney disease. In cases where antibiotics are required, options like beta-lactams may be considered, which have a lower nephrotoxic risk compared to aminoglycosides. However, the choice of medication should always be individualized based on the patient's condition and other co-existing medical issues.