How do chemotherapeutic agents affect the kidneys?
Certain chemotherapeutic agents, including cisplatin and methotrexate, can cause significant renal toxicity. Cisplatin, in particular, can induce AKI by damaging renal tubular cells. Hydration and the use of protective agents like amifostine can help mitigate the renal side effects of these drugs. Regular monitoring of renal function is essential during chemotherapy.
