What are the risks of using aminoglycoside antibiotics?
Aminoglycosides, such as gentamicin and tobramycin, are known for their nephrotoxic potential. These antibiotics can cause acute tubular necrosis, leading to AKI. The risk increases with higher doses and prolonged therapy. Monitoring of drug levels and renal function is crucial when using aminoglycosides, especially in individuals with pre-existing renal impairment.